The blast occurred just as Afghans were breaking their daylong Ramadan fast. The driver of the truck apparently pulled up to the guesthouse, officials said, claiming to bring supplies for the breaking of the fast.
Just as he did so, the truck exploded, bringing down the roof and destroying the building. Photographs on the Tolo News website showed rescuers searching the rubble in the dark for survivors.
In another sign of faltering government resistance and of the Taliban’s steady encroachment on Afghan cities, the insurgents overran an army base at the edge of the provincial capital of Ghazni on Friday night, capturing 25 soldiers.
Also Saturday, in the south, at Kandahar Airfield, a sprawling facility where a small contingent of NATO and American forces were dismantling what remains of their base there, the Taliban ushered in May 1 with an early afternoon rocket attack.
The U.S. military responded immediately to the rocket attack with an airstrike on a Taliban position, a Defense official said.
Fahim Abed and Fatima Faizi contributed reporting from Kabul, Thomas Gibbons-Neff contributed from Kandahar, and Farooq Jan Mangal contributed from Khost.